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As Future Food Companies Look to Grow, A New Crop of Startups Lend a Hand on Biomanufacturing Scale-up

by Michael Wolf
January 27, 2022January 27, 2022Filed under:
  • Alternative Protein
  • Cellular Agriculture
  • Cultured Meat
  • News
  • Precision Fermentation
  • synthetic food
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While companies creating precision fermented and cell-cultured food products continue to raise hundreds of millions of dollars in funding, the reality is their products are still years away from making a significant dent in the overall consumption of a growing global population.

The primary reason for this is that these products still aren’t being produced at nearly the scale they need to feed billions of people. Some estimates have put the biomanufacturing capacity needed by 2030 at 10 billion liters in order to meet the projected demand for fermentation-based animal proteins.

The good news is that a growing number of companies are building out technology and services platforms to help these companies move towards scaled production. One such company is Solar Biotech, which makes customized plant architectures to help future food and other companies scale up their biomanufacturing capacity. The company has been working with startups such as Motif Foodworks and TurtleTree Labs to help them develop their product and move towards higher capacity production.

With Motif, Solar helped them move into pilot production manufacturing for their new plant-based meat ingredient building block, HEMAMI. In partnerships like this, Solar will assist a company with technology transfer of their early products towards higher-scale manufacturing using what it calls its SynBio Hyperintegration Algorithms (SHAs). The end result of its proprietary algorithms is creating customized and modular production facilities built around what the company calls BioNodes.

The partnership worked so well for Motif in developing its HEMAMI product line that the company recently extended its collaboration with Solar.

“The continuation of our partnership will help secure the infrastructure needed to build out Motif’s pipeline of future products,” said Jonathan McIntyre, CEO of Motif FoodWorks, of his partnership with Solar. “Companies like Solar Biotech are an essential link in the move to create a more sustainable food-supply chain that has a positive impact on people, animals and the planet.”

Pow Bio is another company that brings scale-up expertise to new food startups. Pow helps startups building alternative proteins with the necessary fermentation capacity and infrastructure to help move their product concept off the bench and into production scale.

“We have a complete fermentation lab that scales and can take you from a flask you can hold in your hand to 1000L liters of fermentation capacity, which covers the entire ‘pilot’ stage of scale-up,” said cofounder Shannon Hall.

Pow helped alt-cheese startup New Culture take its early lab work and scale-up for pilot production. Before New Culture worked with Pow, their product cost roughly $100,000 to produce a kilogram of cheese. After working with Pow, the company’s product has dropped significantly and is approaching price parity with traditional cheese.

And then there’s Culture Biosciences, a startup that investor Dave Friedberg has described as an ‘AWS for bioreactors’. The company initially started with cloud-connected 250mL stirred tank bioreactors for fast-cycle bench development as a service, and in October of last year took on funding to expand and build out 5L and 250L bioreactors to help move from bench to pilot-scale production.

“Through Culture, we now have the option of a one-stop-shop for bench-scale testing and pilot-scale production,” said Ranjan Patnaik, CTO of alt-egg startup The EVERY Company. “We can develop a process with Culture and easily make a large batch of material. Other benefits include accelerating product pipeline development, data-driven, and lower-risk scaling, and saving them time and money required to build additional fermentation capacity.”

As innovators in the future food industry work on developing their products, these three companies look to play a pivotal role in helping them make the leap. But these three aren’t the only ones, and I expect to see more startups emerge to help fill the biomanufacturing commercialization gap for future food products as investors realize the future food industry doesn’t lack for good ideas, but what it does lack the scale-up and production capacity needed to feed billions of people by 2030.


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Tagged:
  • cell ag
  • Culture Biosciences
  • Pow Bio
  • precision fermentation
  • Solar Biotech

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