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Daily news and analysis about the food tech revolution

cell-based meat

MeaTech Achieves Cultured Meat Milestone by Developing Muscle Fibers from Stem Cells

MeaTech3D, an Israel-based cultured meat startup, announced this week that it had demonstrated progress in the differentiation process from stem cells to muscle fibers.

According to the announcement, MeaTech has achieved the formation of living muscle fibers to a point where they “mirror key characteristics of farm-raised meat.” To achieve the results, MeaTech isolated bovine stem cells, which were then proliferated in the lab. From there, they were able to differentiate these cells into matured muscle cells with improved muscle fiber density, thickness, and length.

This news from MeaTech is just the latest from the startup as they assemble a toolbox of technologies to replicate whole cut animal meat using cell-cultured processes. In September of last year, they announced they had developed a new stem cell manipulation technology that uses plant inputs to transform embryonic mesenchymal stem cells (or eMSCs) into fat cells. That process could be used to replicate intramuscular fat, the fat structures that ribbon through a sophisticated cut of meat such as a ribeye steak. Before that, the company filed for a patent for its technology that 3D prints cell-cultured meat products.

MeaTech isn’t the only group working on developing technology to create muscle fibers via cellular agriculture. Last year, a group of researchers at the University of Tokyo in Japan were able to replicate muscle fibers via cell culture process. The Japanese group achieved a level of elasticity, as the strands contracted in the same way muscle fibers contract.

Alt. Protein Round-Up: Tofurky’s Algae-Based Products and Animal-Free Chicken Fat

In this week’s alternative protein round-up, we have news on MeaTech’s cell-based chicken fat, Impossible Pork, the ProVeg Incubator, Tofurky’s partnership with Triton Algae, and Unicorn Biotechnologies.

MeaTech is now producing animal-free chicken fat

In the race to produce real animal fat outside of the animal, Israel-based MeaTech has hit a milestone: The start-up shared that it is now capable of producing over 700 grams of cell-based chicken fat in a single production run. MeaTech acquired Belgium start-up Peace of Meat last year, and is using its platform to produce the cell-based fat. The fat product can be used to create realistic marbling in cell-based meat or even used to create a plant-based hybrid product.

Impossible Foods is bringing its alt. pork product to foodservice

Impossible Pork will soon be found in foodservice locations in the U.S., Singapore, and Hong Kong. As of this week, David Chang’s New York restaurant Momofuku Ssam Bar began serving the alternative pork product in one of its dishes. Impossible Pork is set to launch in 100 plus restaurants in Hong Kong starting October 4th, and in Singapore sometime before the end of this year.

Proveg Incubator announces eight new start-ups in cohort

Berlin-based ProVeg Incubator just kicked off its latest accelerator program on September 20. Through the incubator, the start-ups have access to one-on-one mentoring, ProVeg’s network, and up to €250,000 in funding. This food-tech focused cohort contains eight start-ups from around the world, including:

  • Altein Ingredients (India) – mung bean protein
  • Alt Foods (India) – Plant-based milk made from grains and sprouted millet
  • Brain Foods (Bulgaria) – Plant-based snacks
  • Cultivated Biosciences (Netherlands) – uses fermentation to make a fat ingredient from yeast
  • Genesea (Israel) – B2B food-ingredient company that uses macroalgae
  • Meat Future (Estonia) – mycoprotein chicken and fish
  • Plant-based Japan (Japan)
  • ProProtein (Estonia) – uses precision fermentation to create dairy proteins

Tofurky partners with Triton Algae for future alt protein products

Plant-based meat brand Tofurky announced that it has partnered with algae producer Triton Algae Innovations to develop a new line of plant-based alternatives. The products will be crafted using Triton’s “essential red” algae, which contains protein, iron, vitamin A, and more. The algae, which is normally green, is grown with UV light which causes it to turn red and produce heme. It was not disclosed what exactly the new product will be, but it is set to launch in the first quarter of 2022.

Unicorn Biotechnologies Is Making Purpose-Built Bioreactors for Cell-Based Meat Production

According to Jack Reid, the CEO a new Cambridge-based startup called Unicorn Biotechnologies, companies trying to make meat without the animal today are mostly using large metal vats built for making something other than meat. “Existing bioreactor systems haven’t been and weren’t developed specifically for the cell ag industry,” said Reid. Read The Spoon’s story about how Unicorn is working to build purpose-built bioreactors for cell-based meat here.

Unicorn Biotechnologies Is Making Purpose-Built Bioreactors for Cell-Based Meat Production

Jack Reid believes that the cell-based meat industry could move a lot faster if it just used manufacturing equipment made for the job.

According to the CEO of a new Cambridge-based startup called Unicorn Biotechnologies, companies trying to make meat without the animal today are mostly using large metal vats built for making something other than meat.

“Existing bioreactor systems haven’t been and weren’t developed specifically for the cell ag industry,” said Reid.

That’s right. In an industry where hundreds of millions of dollars in venture funding has flowed into companies that are predicted to be someday worth billions of dollars, startups are using equipment ill-suited for the task at hand. Instead of using machines made to replicate animal cells at scale, these companies are using bioreactors optimized to create products already produced in large volumes and have established markets.

“We’re talking about large fermenting systems that are for brewing beer,” said Reid. “Or even pharmaceutical grade bioreactors that are designed for vaccine manufacturing and recombinant protein production.”

By using equipment that is not purpose-fit for replicating animal cells for cultured meat products, Reid thinks a massive amount of inefficiency and cost is added to the process. Pharma bioreactors don’t have the right sensors and are built to make a smaller amount of product at a much higher cost. Beer fermenters are built, well, to make beer. But the biggest problem in Reid’s mind is using systems that aren’t built for cell-based meat means you ultimately have unhappy cells.

“Most bioreactors have a long period optimization period where you have to figure out how to make the conditions just right to make the cells happy and to allow them to proliferate, differentiate and turn into the fat, muscle,” said Reid.

And making the cells happy is a challenge cell-based meat makers need to address at each phase of the process. This can mean optimizing the process on the research bench, during pilot production, and ultimately for fully scaled manufacturing.

If this sounds like a problem for an industry hoping to make enough product to account for a significant percentage of the overall meat market by the end of the decade, it is. But Reid and his co-founder Dr. Adam Glen think they have a solution: a modular manufacturing system built for cell-based meat production.

Why modular? Because as Reid describes it, with a modular bioreactor system, the transfer of the highly technical process for making a cell-based meat product would only need to happen once, from the lab bench to their bioreactor. After that, a company could scale up production by simply adding more modules.

“The path to scaling up your production capacity is going from one module to two, ten, one hundred, and so on until you reach your desired output.”

How would it all work? According to Reid, like a bunch of robots working together.

“A good parallel might be swarm robotics,” said Reid, who pointed to the example of robotic systems used in large grocery warehouses. “In those, we’re not looking at 100 different robots acting together. We’re looking at one system with 100 different ways to interact with the warehouse. That is the principle that underpins our technology and our modular system.”

By having a highly flexible system that can fit various sizes of producers, Reid thinks his systems could bring cell-based meat-making to a more widely distributed group of future meat manufacturers.

“We’d like it to be a reality where smaller manufacturing systems are a realistic possibility,” said Reid. “To bring to individual farms, to bring to communities, and really to spread the manufacturing of these products away from the highly centralized production model that has dominated protein manufacturing for the last few decades.”

But before all this happens, Reid and his team need to build the product and get it ready for manufacturing. The company, which took on a pre-seed funding round from SOSV/HAX and Entrepreneur First, is currently building its product prototype in the labs.

“Once we’ve hit a few more of our milestones, we’re looking to go out and do our next round of fundraising, scale up the team, and transform our prototype it into the first generation of our product.”

Wild Earth Launches Cell-Based Pet Food As It Raises a Fresh $23 Million

Plant-based pet food brand Wild Earth has announced plans to expand its product line into pet food made with cell-based meat. The announcement comes on the heels of a new $23 million funding round from a group of investors that includes Mark Cuban and the star of Vampire Diaries, Paul Wesley.

Led by alternative protein entrepreneur and investor Ryan Bethencourt, Wild Earth has been one of the early leaders in creating pet food from plant-based ingredients. With products like Clean Protein dog food (which uses pea and potato protein) and Superfood Dog Treats With Koji (Koji is a fungi protein used in fermented food in Asia), company sales have grown more than 700% year over year, according to a release sent to The Spoon.

And now, the company plans to use cell-based meat in a new line of products. From the release:

(Wild Earth) has its sights set on adding new products and launching a new initiative into cell-based meat pet food to deepen their market share and gain new customers. Cell-based meat is a lab-grown meat; a sustainable alternative to traditional meat. Cell-based meat is cruelty-free to produce. Cell-based meat is the future of meat, and pet food is leading the revolution!

The company got a boost in 2019 when Bethencourt appeared on Shark Tank and secured a $550 thousand investment from Cuban. Bethencourt, already well-known in the alternative protein space as one of the earliest employees at seminal biotech accelerator IndieBio, became an influential alt-protein evangelist and helped increase Wild Earth’s profile in the market.

Wild Earth is just one of a number of pet food companies eyeing cell-based meat as an ingredient. Startup Because Animals is working on cat food with meat made from mice cells which it plans to have in the market by 2022. Boulder-based Bond Pet Foods has sourced chicken cells from a heritage hen named Inga and plans to roll out pet food using cultured chicken meat in 2023.

And now, we can add cell-based beef and seafood to the list of ingredients coming to the cell-based pet food market. According to the release, Wild Earth plans to have its new lineup of pet food with beef, chicken, and seafood cell-based meat inputs on the market in 2022.

You can see highlights from Bethencourt’s appearance on Shark Tank in the video below:

Mark Cuban Invests In Vegan Dog Food Company Wild Earth

The USDA Is Seeking Comments About What to Call and How to Label Cell-Based Meat

It looks like the US government is getting serious about putting cell-based meat on consumer plates.

That’s because on Thursday, the USDA’s Food Safety and Inspection Service (FSIS) announced it had opened a 60 day period in which it will solicit comments to questions put forth in an advance notice of proposed rulemaking (ANPR).

Some of the topics/questions the FSIS is looking for feedback on include (italicized text excerpted from the notice):

Product name: “Should the product name of a meat or poultry product comprised of or containing cultured animal cells differentiate the product from slaughtered meat or poultry by informing consumers the product was made using animal cell culture technology? If yes, what criteria should the agency consider or use to differentiate the products? If no, why not?

Terminology: What term(s), if any, should be in the product name of a food comprised of or containing cultured animal cells to convey the nature or source of the food to consumers? (e.g., “cell cultured” or “cell cultivated.”)

What do about hybrid farmed/cell-based: If a meat or poultry product were comprised of both slaughtered meat or poultry and cultured animal cells, what unique labeling requirements, if any, should be required for such products?

Can cell-based meat use meat terminology to describe products? Should terms that specify the form of meat or poultry products (such as “fillet”, “patty”, or “steak”) be allowed to be included in or to accompany the name or standard of identity of foods comprised of or containing cultured animal cells?

I expect this process to be somewhat contentious. The powerful lobbying group, the National Cattlemen’s Beef Association (NCBA), has shown it’s not a fan of cell-based meat production and will certainly have some thoughts to share during this process. Opponents can be expected to claim that applying terms and product names familiar to consumers from their consumption of traditionally farmed meat to cultured meat will be misleading.

This most recent move by the USDA is part of a process kickstarted way back in 2018 when the USDA and the FDA announced they were beginning to develop regulatory frameworks for the cell-based meat industry.

The division of oversight described in the initial announcement is referenced in yesterday’s announcement:

Under the agreement, FDA will oversee cell collection, growth, and differentiation of cells. FDA will transfer oversight at the cell harvest stage to FSIS. FSIS will then oversee the cell harvest, processing, packaging, and labeling of products.

Since those early days in 2018, cell-based meat has moved off the bench and into pilot production across the globe. Countries like Singapore have outpaced the US in opening regulatory glide paths for making cell-based meat available to consumers. Hopefully this news is a sign that the day when we can buy cell-based meat in the US will be here soon.

Full Interview: Future Meat’s Koby Nahmias Talks Cell-Based Meat Production

Six years later, his company Future Meat Technologies regularly makes news for reaching ever lower price milestones for his cell-based chicken. And according to Nahmias, he’s only getting started.

The following is my full conversation with Nahmias.

Subscribers to Spoon Plus can get access to this full interview. You can learn more about Spoon Plus here. 

Eat Just Partners with Qatar Free Zones to Bring Cultured Meat Facility to the MENA Region

Eat Just announced today that it has partnered with Doha Venture Capital (DVC) and Qatar Free Zones Authority (QFZA) to build a cultured meat facility in the Middle East and Northern Africa (MENA) region.

The new facility will be located in the Umm Alhoul Free Zone in Qatar, and will at first house Eat Just’s cultured meat division, GOOD Meat. Eventually, the facility will accommodate Eat Just’s plant-based egg brand JUST Egg as well. In addition to those brands, the facility will also conduct research and development, engineering, and business development.

According to the press announcement, the Qatar Free Zones Authority and Qatar’s Ministry of Public Health have indicated that they will grant regulatory approval for GOOD Meat’s cultured chicken “very soon” and have formally granted an expert license for the cell-based meat. If Qatar does come through with this approval, it would be the second region in the world to approve the sale of cultured meat, following Singapore’s decision to do so in December of last year.

Gaining regulatory approval in more countries around the world is obviously a key milestone that needs to be reached in order for cultured meat to gain any sort of traction. Cell-based meat startups around the world have raised a ton of money over the past year, and the technology is rapidly maturing. But all the funding and the best technology in the world doesn’t mean anything if you aren’t allowed to sell your product.

While there are skeptics that doubt cell-based meat will ever be able to economically scale, a number of startups have made moves that aim to bring it to market. After two drastic price reductions this year, the production price of Israel-based Future Meat’s cell-based chicken is now $4 for 110g (check out our recent podcast interview with Future Meat Founder and CSO Yaakov Nahmias for more). Here in the U.S. Memphis Meats re-branded to the more consumer-friendly UPSIDE Foods and announced a partnership with the Altier Crenn restaurant in San Francisco.

Eat Just has definitely pushed its way to the front of the cultured meat pack, however. It is the first company to ever commercially sell its cultured meat, and now it will have large-scale production facilities in both Singapore and Qatar.

Koby Nahmias Knew Cell-Based Meat Had Huge Potential But Was Too Expensive. He Set About Changing That.

Something was bothering Yaakov Nahmias.

The longtime bioengineer had been sitting alongside the Charles River near MIT drinking coffee when he got a call from an investor in Israel who wanted to know what he thought about Mark Post’s famous quarter-million euro hamburger.

“I told him, it’s probably the silliest idea I’ve ever heard,” said Nahmias, who also goes by Koby, in an interview with The Spoon.

It wasn’t the science itself Nahmias thought was silly – the longtime bioengineer knew making a burger in a lab was an impressive scientific feat – but rather the idea that consumers would pay hundreds of dollars, let alone hundreds of thousands, for a burger no matter how science-forward meat the meat is.

Sitting there, Nahmias began to think about what it would take to bring down the cost of growing meat in a bioreactor to result in prices approachable enough for the average consumer.

It wouldn’t be easy. As the founding director of the Alexander Grass Center for Bioengineering at the Hebrew University of Jerusalem and a longtime consultant to the pharma industry, Nahmias knew that this type of complicated biotech cell-reproduction work was hugely expensive and – the way things were structured back in 2015 – totally impractical for producing low-cost consumables.

Yaakov “Koby” Nahmias

But Nahmias also thought that maybe it didn’t need to be this way. After all, he had colleagues who ran an insect farm, which had a much lower cost per unit of biomass produced. So why, he wondered, was creating meat using cellular agriculture so much more expensive than other forms of biomass production?

One reason was that cells produced make a lots of toxins like ammonia. And, unlike insects which have livers to remove these toxins, cells produced in bioreactors “essentially grow in their own urine,” Nahmias said.

When he looked around for systems are good at ammonia removal, the obvious example was the aquarium.

“If you’re growing fish, and and you are giving them too much food, there is too much protein that breaks down into ammonia,” said Nahmias. “The only way to treat it is by adding zeolites that will bind the ammonia relatively fast. So using that type of insight, you can design a process that will do it at scale.”

Another early insight Nahmias had was that pharma bioreactors often grew one type of animal cell – hamster ovary cells – which are commonly used for vaccine development. While hamster cells grow easily in traditional bioreactors, that’s not the case with meat like beef or chicken.

But perhaps the biggest challenge Nahmias saw was the cost of growth medium used to feed the cells. After consulting to the pharma industry for the last decade, he knew it took about 10 liters of culture medium to make 1 kilogram of biomass. At what he estimated to be $20 per liter for medium at that time, he thought even with the world’s most advanced tech, they’d start hit a cost floor of around $200 per kilogram.

He would spend the next six months focused on reengineering the process of cell-based meat production. But this was only the beginning. Nahmias knew that it would take some time to commercialize his work.

So not long after, he would start a company called SuperMeat with a couple of other cofounders, where he further developed these early ideas. That company would eventually split up a year later and Nahmias would go on to found his current company, Future Meat Technologies, where he set about creating a scaled system for making low-cost cell-based meat.

Fast forward to today and he’s doing just that. Future Meat regularly makes news about reaching ever lower prices for its cell-based chicken, which is why I wanted to talk to him about how he achieved cost milestones that many have thought wouldn’t be achievable for at least half a decade.

You can listen to my full interview with Nahmias on the latest episode of The Food Tech Show. Just click play below or get the episode at Apple Podcasts, Spotify or wherever you get your podcasts.

Japan’s CulNet Consortium, an ‘Open Innovation Platform’ for Cell-Based Meat, Officially Launches

Last week a group of Japan-based companies announced the official launch of the CulNet Consortium, an open innovation platform for the development of cell-cultured meat in Japan and beyond. The announcement, made by Japan cell-based meat startup IntegriCulture, details the member companies and outlines the activities of the group.

The group’s platform is centered around an open innovation framework developed by IntegriCulture, one of Japan’s most visible and active startups in cellular agriculture. The Uni-CulNet framework and the Consortium plans were originally announced in May of 2020, when IntegriCulture described the framework as “a standardized cellular agriculture infrastructure” that “rapidly establishes the foundation for democratized cellular agriculture.”

The consortium’s member companies plan to cooperate across five different areas to help accelerate the sector’s overall advancement: cell source, culture medium, CulNet hardware, product bioreactor, and product processing.

From the release:

  • Standardized culture media: Recipes that are fundamentally different from the existing media (basal media). Basal media are the raw material for all cultured cell products, and a different type is required for each kind (food, material, medical, etc.).
  • CulNet SystemTM hardware: Hardware that lets people use the CulNet SystemTM across a broad spectrum of uses, whether it’s in mass production or just at home.
  • Product bioreactors: Bioreactors that are used to make things like the products’ edible parts. We estimate that a variety of animals used as agricultural products will be a source for the cells.
  • Cell product processing: The process control that is needed to meet the products’ processing and safety requirements (cell components and culture supernatant).
  • Cell sources: The process that is used to extract and culture cells from livestock and fishery resources and the systems that enable the whole sequence of processes to be completed right where the cell sources are produced—tailoring them to their intended use, source animal species, etc.

It’s not surprising IntegriCulture and its founder Yuki Hanyu are a driving force behind a standardization push around open innovation. Hanyu has been the most visible evangelist for cell-based meat in Japan over the last few years, and his company’s ethos for open innovation was signaled by the efforts he put into building a DIY cultured meat initiative with the Shojinmeat project.

The CulNet Consortium isn’t the only industry organization gaining momentum as the cell-based meat industry matures. The Alliance for Meat, Poultry & Seafood Innovation (AMPS Innovation), an industry group focused on market education and industry advocacy, just announced an eighth member, Orbillion Bio, who joins Eat Just, Upside and Blue Nalu, among others. AMPS has been working to influence US policy to support the cultured meat industry, including a recent joint industry letter to the FDA after its call for input into the labeling framework for cell-based meat.

South Korea: Seawith Uses Algae for Serum and Scaffolding in Cultured Meat

It’s been a banner year so far for cultured meat. In addition to all of the funding that’s been flowing into the space since the start of 2021, there is also a growing number of startups from around the world attacking the issues of creating cell-based meat in unique ways.

The latest such startup to come to our attention is South Korea’s Seawith, which is leveraging algae to differentiate itself from other cultured meat players. The company uses algae to replace the fetal bovine serum (FBS) that has historically been used as a growth medium for cells. FBS is expensive and controversial, so most cell-based meat startups we cover are developing technologies that don’t require it. But Seawith is also using algae as a scaffolding to grow meat, which the company says yields thicker “cuts” of meat.

Following is a brief Q&A conducted via email with Heejae Lee, CTO of Seawith, who provides a little more insight into the company and what it is creating. Answers have been lightly edited for clarity.

1.) What makes Seawith different from other cell-based meat companies?
Seawith has the distinction of making the world’s first perfect steak at a price similar to slaughter meat. Based on algae engineering technology, it has replaced most of the bovine serum, which accounts for more than 90 percent of the cost of culturing meat, and the cell culture scaffold technology can make cultured meat thicker than 1cm.

2.) What makes algae so useful in creating cell-based meat?
The key principle of cultured meat is that one muscle cell takes nutrients and synthesizes them to make large meat. Algae is rich enough to be used as a nutritional supplement, which allows efficient cell culture by supplying it to cells. Also, algae are one of the most abundant resources on Earth, and they have the advantage of being cheap and available everywhere because they can grow anywhere with water and sunlight.

3.) Where are you at with your product right now?
We just finished our research and held a cultured meat tasting event. Cultured meat made with Korean bovine cells was evaluated well by attendees, who said it had the taste and aroma of beef, and the texture of meat could be seen. Currently, it is a muscle-only culture, but we are preparing various features such as taste of fat cells. We are preparing to get permission to produce enough to supply large quantities of products to restaurants by 2023.

4.) What types of cell-based meat will you be creating?
Seawith is making beef steak. There are many different types of meat, but the reason why we are making
difficult steaks is that only the technology we have can implement them. After perfecting the texture of muscle tissue, we plan to develop various meat products such as chicken, pig, and fish as well as meat products and animal feed.

5.) What is your timeline to bring your product to market?
We are currently discussing with the Ministry of Food and Drug Safety to make a trial sale in Korea with the aim of
launching a restaurant at the end of 2022. To this end, we are planning an urban cultured meat factory and will introduce a minimum production model by 2021. From 2023, we are preparing for local tasting event and product launch in different locations such as North America and Singapore.

Full English: Ivy Farm Aims to Launch Cell-Based Sausages by 2023

Add Ivy Farm Technologies to the growing number of startups around the world creating cell-based meat. Ivy Farm announced itself at the end of last week, saying it plans to produce cultured sausages for markets and restaurants by 2023.

U.K.-based Ivy Farm Technologies is a spin-off from Oxford University, where co-founders Dr. Russ Tucker and Professor Cathy Ye met at the school’s Department of Engineering Science. Oxford provided the source of Ivy Farm’s key technology as well as seed funding through the University Challenge Seed Fund.

Like most cell-based meat companies, Ivy Farm uses a small number of cells taken from an animal and places those cells in a bioreactor, where they are grown and multiplied into meat. According to a press announcement sent to The Spoon, Ivy Farm says its technology is a “game changer” because of “a unique ‘scaffold’ system where the cells grow.” UPDATE: In an email Ivy Farm said that it’s approach to scaffolding involves creating a special surface that allows for the “continuous harvest” of cells (there’s no need to stop the system), at a lower cost vs. other technologies. Oxford owns the technology and has licensed it out to Ivy Farm.

The company wasn’t more specific about its scaffold technology (we reached out to them for more informationSee Update above), but focusing on different scaffolding techniques certainly isn’t unique for an alternative protein startup. Matrix Meats, Ecovative, and NovaMeat all tout different solutions to scaffolding alternative meats.

Ivy Farm’s goal of selling its cultured meat in stores and restaurants by 2023 is certainly ambitious seeing as the only country to approve the sale of cultured meat so far has been Singapore. Additionally, Ivy Farm is only now kicking off its fundraising, with the goal of raising raising £16m (~$22.5M USD) to create an R&D facility. That’s a lot to accomplish in less than two years.

Ivy Farm isn’t the only cell-based meat startup in the U.K. to get funding this year, or the only startup to be spun out of a university there. CellulaREvolution, which raised £1 million (~$1.37M USD at the time) in February, was borne out of research done at Newcastle University. CellulaREvolution has developed a synthetic peptide coating and smaller footprint bioreactor.

We are all for more startups developing cell-based meat, especially ones with big ambitious goals. Ivy Farms is certainly ambitious, now we’ll have to see if its technology can match its claims.

Memphis Meats Re-Brands as UPSIDE Foods, Announces Cultured Chicken as its First Product

Memphis Meats, one of the older cell-based protein startups, announced today that it has rebranded and is now UPSIDE Foods. Perhaps more important, the company also announced that its first consumer product, cultured chicken, will be available to customers this year… pending regulatory approval.

Founded in 2015, UPSIDE Foods cultivates animal protein without the need to raise animals. The company is working on cell-based versions of different kinds of meat, but said in today’s press announcement that it chose chicken as its first product because of its versatility in recipes and culinary applications, as well as its appeal across geographic regions.

To make its cell-basd meat at scale, UPSIDE has broken ground on a production facility in the San Francisco Bay Area. The full-stack facility will produce, package and ship cultured meat at what the company says is a larger capacity than any other cell-based meat company.

Back in 2019, UPSIDE told The Spoon that the company was holding off on establishing a concrete launch date for their cultivated meat until they could guarantee their product was tasty and scalable, and until regulatory frameworks were established. This last bit was echoed in today’s press release with the “pending regulatory approval” caveat. So far, Singapore is the only country that has approved the sale of cultured meat. There hasn’t been as much clarity here in the U.S., though execs at cultured meat startups are hopeful approvals will be granted in the next two years.

We are definitely entering into a new phase in the evolution of cultured meat. A number of cell-based startups around the world have received funding this year, including CellulaRevolution, CellMeat, Mirai Foods and New Age Meats. In addition to more funding, UPSIDE and other established cultured protein startups like BlueNalu and Avant Meats are opening up their own production facilities to scale up the manufacturing of their meat.

It’s also worth noting that UPSIDE’s chicken announcement comes during the same week that Future Meat said it has dropped the production price of its cell-based chicken by 50 percent. In an interview with Plant Based News, Future Meat CEO, Rom Kshuk said it now costs $4 to produce 110 grams of its chicken, and that price should drop to $2 over the next year and a half. Reaching price parity with conventional animal meat will be a key factor in the success of cultured meat.

Along with a new identity, UPSIDE also announced a new investor today. Whole Foods CEO, John Mackey, has invested an undisclosed sum in UPSIDE.

UPSIDE’s new name and look also reflects the company moving into its own next phase as it advances beyond research and into commercial production. If you’re interested in seeing how it all began with the company, I recommend watching the documentary Meat the Future, which chronicles the rise of Memphis Meats from its very early days through much of its growth.

Meat The Future (2020) I Official Trailer I MetFilm Sales