• Skip to primary navigation
  • Skip to main content
  • Skip to primary sidebar
  • Skip to footer
  • Skip to navigation
Close Ad

The Spoon

Daily news and analysis about the food tech revolution

  • Home
  • Podcasts
  • Events
  • Newsletter
  • Connect
    • Custom Events
    • Slack
    • RSS
    • Send us a Tip
  • Advertise
  • Consulting
  • About
The Spoon
  • Home
  • Podcasts
  • Newsletter
  • Events
  • Advertise
  • About

TurtleTree Scientific

March 30, 2021

TurtleTree Scientific Partners With JSBiosciences to Develop Cell Culture Media at Commercial Scale

TurtleTree Scientific, the B2B arm of cellular ag company TurtleTree Labs, announced today a new partnership with JSBiosciences to collaborate on the development of cell culture media. The overarching goal of the partnership is to bring down the cost of production for cell-cultured products in order to eventually achieve commercial scale.

Singapore-based TurtleTree Labs is best known for its technology that produces human milk from mammalian cells. The company launched its TurtleTree Scientific arm earlier this year with the goal of creating food-grade growth factors for cultured protein products.

Finding a growth media that is accessible, affordable, and that doesn’t rely on animals to get remains one of the biggest challenges for cultured protein companies. Some companies are now trying to distance themselves from the use of the controversial fetal bovine serum (FBS), but alternatives are few and far between, not to mention wildly expensive. 

JSBiosciences is a valuable partner in this area because it already has a successful track record of developing mammalian cell culture media at a large scale. The company will provide TurtleTree with food-grade basal media and media formulation services, with the goal of getting “upstream” production costs low enough to allow for commercial-scale production of cell-cultured products, starting in Singapore.

This is the second major partnership for TurtleTree Scientific so far in 2021. Last month, the company announced a collaboration with biotech company Dyadic International. Through that partnership, the two companies are developing recombinant food-grade growth factors for proteins that can be grown in high yields at lower costs in bioreactors.

February 2, 2021

TurtleTree Scientific and Dyadic to Develop Affordable Growth Factors for Cell-Based Proteins at Scale

TurtleTree Scientific, the recently launched B2B unit of TurtleTree Labs that develops growth factors for cellular ag, today announced a “fully funded” collaboration with biotech company Dyadic International. Through this partnership, the two will develop recombinant food-grade growth factors for proteins that can be grown in high yields at lower costs in bioreactors. This could allow TurtleTree, which makes cell-cultured products (including human breastmilk) to scale up and get to market faster, paving the way for cultured meat and dairy companies to do the same.

Dyadic is known for its its C1 gene expression based on the Thermothelomyces heterothallica fungus. Via this platform, Dyadic can produce recombinant proteins at an industrial scale of up to 500,000 liters, with lower capital and operating expenditures than what cultured meat companies would normally find. The company’s tech has been used by some of the world’s most well-known biotech companies, including DuPont and BASF.

In a statement, TurtleTree cofounder and Chief Strategist Max Rye said that manufacturing human growth factors both at scale and at an affordable cost has been a major challenge, and that the partnership with Dyadic will help the company “overcome this hurdle” safely and efficiently.

Growth factors account for the bulk of the cost in cell-based protein production — 55 to 95 percent, by some accounts. Part of the reason for this, TurtleTree explained last month, is that cell culture media components have been developed for non-food areas like research and theraputics, which do not have the same scale requirements and cost constraints as food and agriculture production.

Ronen Tchelet, PhD, Dyadic’s Vice President of Research and Business Development, said in today’s press release that the company will engineer “hyper-productive” C1 cel lines to develop high bioactivity and yields suitable for commercial-scale productions. This will not only accelerate the timeline for TurtleTree’s business, it could also, according to Rye, “make cellular agriculture a reality for all” by enabling food-grade growth factors at an affordable price point to the wider cellular ag industry.

Primary Sidebar

Footer

  • About
  • Sponsor the Spoon
  • The Spoon Events
  • Spoon Plus

© 2016–2025 The Spoon. All rights reserved.

  • Facebook
  • Instagram
  • LinkedIn
  • RSS
  • Twitter
  • YouTube
 

Loading Comments...